According to her Wikipedia article, she was wife number two for Holy Roman Emperor Maximilian I whom she married in 1494. He was also husband number two for her. Her first marriage was childless when her husband, Duke Philibert I of Savoia, died when she was age ten. He sired a number of children between 1494 and when she died in 1510, but none with her.
Grand Ladies
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ca. 1555 Caterina de' Medici by ? (Galleria degli Uffizi - Firenze, Toscana, Italy)
Ritratto di Isabella d'Este by Leonardo da Vinci (Musée du Louvre - Paris, France)
1493-1495 (between) Ambrogio de Predis workshop Bianca Maria Sforza (Kunsthistorisches Museum - Wien, Austria)
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