She was the daughter of Infanta Catalina. Her Wikipedia article is here. She bore 14 children and died bearing the fourteenth who survived her mother.
Grand Ladies
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ca. 1555 Caterina de' Medici by ? (Galleria degli Uffizi - Firenze, Toscana, Italy)
ca. 1586 Isabel Clara Eugenia with Magdalena Ruiz by the studio of Alonso Sanchez Coello (Museo Nacional del Prado - Madrid, Spain)
Isabella of Savoy by Safonabisa Anguisola (private collection)
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